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The assay buffer consisted of 20 mM HEPES (pH 7.5), 100 mM NaCl, 2 mM MgCl, and 1 mM TCEP

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These considerations set the stage for todays Lasker~Debakey Clinical Medical Research Award, as we recognize three scientists, Svetlana Mojsov, Joel Habener and Lotte Knudsen for their remarkable discoveries that have resulted in the development of revolutionary medicines that safely lower blood glucose in diabetics and induce profound weight loss that reduces obesitys comorbidities

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